ADIPOQ

Owned by Roberto Barrero Gumiel
Oct 21, 2021
25 min read

The data collected for both healthy and unhealthy horses for the ADIPOQ genomic locus was processed using the nextflow ConsGenome pipeline (eResearch).

Genomic Locus

GENE

Chr: coordinates

Length

%GC

Number of exons

GENE

Chr: coordinates

Length

%GC

Number of exons

ADIPOQ

Chr 19: 27,250,419 - 27,252,552

2,134 bp

47.75%

2

Chr

Source

Feature

Start

End

Strand

version

Description

19

ensembl

gene

27250419

27252552

+

.

gene_id "ENSECAG00000002962"; gene_version "3"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding";

19

ensembl

transcript

27250419

27252552

+

.

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding";

19

ensembl

exon

27250419

27250803

+

.

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "1"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding"; exon_id "ENSECAE00000012364"; exon_version "3";

19

ensembl

CDS

27250419

27250803

+

0

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "1"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding"; protein_id "ENSECAP00000002024"; protein_version "2";

19

ensembl

start_codon

27250419

27250421

+

0

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "1"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding";

19

ensembl

exon

27251674

27252552

+

.

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "2"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding"; exon_id "ENSECAE00000012418"; exon_version "2";

19

ensembl

CDS

27251674

27252191

+

2

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "2"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding"; protein_id "ENSECAP00000002024"; protein_version "2";

19

ensembl

stop_codon

27252192

27252194

+

0

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; exon_number "2"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding";

19

ensembl

three_prime_utr

27252195

27252552

+

.

gene_id "ENSECAG00000002962"; gene_version "3"; transcript_id "ENSECAT00000002827"; transcript_version "3"; gene_name "ADIPOQ"; gene_source "ensembl"; gene_biotype "protein_coding"; transcript_name "ADIPOQ-201"; transcript_source "ensembl"; transcript_biotype "protein_coding";

Pipeline overview:

  • Mapping onto ADIPOQ genomic locus

  • Build a consensus genomic sequence for each horse based on the mapped genomic data

  • Predict nucleotide variants for each of the horse samples

  • Compare the sequence similarity of the Equus_caballus’s ADIPOQ gene locus (EquCab3.0; chr19_pos:27250419-27252552) vs each consensus sequence derived for each horse

Results

Consensus sequences for each horse:

>AP01_healthy_ADIPOQ chr19_pos27250419-27252552 ---------------TC-GGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCATTCAACCACACCATGCACACCTCCTGCAGCTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAGGCTTCAAAGAGGAGGCA---------------------------------G--T-A-CC-G-A---A-AGGG-TGGGGGCATGGAGGG-CTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCYTCAAGAGTCTGGRTGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCC----------------------------------- >AP02_healthy_ADIPOQ chr19_pos27250419-27252552 -TGGGACAATGTG-CTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCATTCAACCACA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACA-AAGAGCAAAAGTACRGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCCA---------- >AP07_healthy_ADIPOQ chr19_pos27250419-27252552 ------------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCAT-------------------------------------------------------------------------------------------------------------------------------------------------------------------A--ACAG-G-G----TGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAG-GG-GGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG >AP08_healthy_ADIPOQ chr19_pos27250419-27252552 ------------------------CTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAYGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGAC------------------------------------------------------------------------------------TTTCTCCTCATTTCCACTTAATTCCCATTCCA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAAGGCTTCAAAGAGGAGG-AGGGCAGAGGGAACAGAA---------------------------------------------------------------GAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTC-CATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAG---------------------------------------------------------------- >AP10_healthy_ADIPOQ chr19_pos27250419-27252552 -------------TCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCC-C-TC-ATCCATCCC---TCC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGGAG--A-----------------------------------TT-AGCCAGCACATAAAGGG-TGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCYTCAAGAGTCTGGRTGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGA-T-TCAGAT--------------AC---------------------------------------------------------------------- >AP12_healthy_ADIPOQ chr19_pos27250419-27252552 ------------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTtgtgcgtacatgtGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCAACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AATGCAGGCC---------------------------GAGGCAGGGCAGAGGGAACAG------------------------------------------GGGGGCAT-----------------------T-GG-GAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATG--------------------------------------------------------------------------------- >AP15_healthy_ADIPOQ chr19_pos27250419-27252552 -----------------------------TAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCT-T-TCT-CATCA--CTCCCCATCTCCTTTCCC-CCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCATTCAACCACACCATGCACACCTCCTGCAGCTC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATGATGG-GACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGAC-TGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCCAGTCCTG---- >AP20_healthy_ADIPOQ chr19_pos27250419-27252552 ---------TGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGCGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATC--T-TTCCC-A-CT-TT-AT-TTCTT-TT-CTCCTCATTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GACAAATGTCCAAGGTATAGAACAGAGAGAAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGGG--GGGGGC-TGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCTTCAAGAGTCTGGGTGTATTGGCAATGA-AGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAG---------------------------------------------------------------- >MC01_healthy_ADIPOQ chr19_pos27250419-27252552 --------------------------------------------CTATGTGTGTGTGTGTGCTTGTGCGT-CATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGCT-CAAAGAGGAGGCAG--------GAACAGAAGAGCAA-AGTAC-GTTGGTTGAG------------------------------------------GACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGT-AAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAA-C-AC-A--AAG-CTTCG-CAAT-C------------------------------- >MC03_healthy_ADIPOQ chr19_pos27250419-27252552 ---------------TCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCC-A--CTG-T--T-TTCT-ATTTCTCCTC--TTCC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAGAGAAAATG-------TGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGC-AGCACATAAAGGGTTGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGG-CGTGAAACTCTCC-CTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTARCCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGA-AGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCC-GTC--G-G-- >AP03_unhealthy_ADIPOQ chr19_pos27250419-27252552 ------------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCA-CCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGC-CTATCTAC-TCACCCTC-CCA-C-CCT---CC-CCCCC-C-T-C-T---T------------TCT--T-ATATT-TTA-T--TC------TCCA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-GGCAGGGCAGAGGGAACAG-----------------------------------AAGGG----GGGCATGGAGGGTCTATGATGGAGACTTATAGG-GAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTARCCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCYTCAAGAGTCTGG-TGTATTGGCAATGAAAGGATGGTAAC----------------------------------------------------------------------------------------------------------- >AP04_unhealthy_ADIPOQ chr19_pos27250419-27252552 --GGGACAATGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAYGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATSTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCATTCAACCACACCATGCACACCTCCTGCAGC-CACTGTCCTTCTCTTGGAGAACTCTTGGTCTACTCACGAAGACAAATCTAATGCACAAGGCTCTGTT-GA-GTTACTACAAGGAAGTTCACTCCAAATATGCCAAGTCCAACGTGGACAA-TGTCCAAGGTATAGAACAGAGAGAAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACRGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG >AP14_unhealthy_ADIPOQ chr19_pos27250419-27252552 -TGGGACAATGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAGTGGCATTCAACCACACCATGCACACCTCCTGCAGCTCACTGTCCTTCTCTTGGAGAACTCTTGGTCTACTCACGAAGACAAATCTAATGCACAAGGCTCTGTTAGAGGTTACTACAAGGAAGTTCACTCCAAATATGCCAAGTCCAACGTGGACAAATGTCCAAGGTATAGAACAGAGAGAAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATGGAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCCCTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG >AP17_unhealthy_ADIPOQ chr19_pos27250419-27252552 ------------------------------------------GACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGAC-AGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAG-TGTTATCTGTAAAACCAGTGCCATTGAC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAAGGCTTCAAAGAGGAGG---------GGGAACAGAAG-GC-AAAGT-C-GTTGG--GAG----------------------------------------------------------------------------------------------------AGGAGGACGT----------CCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCC-TTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTA-TCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAA---------------------------------------------------------------------------------------------------------- >AP18_unhealthy_ADIPOQ chr19_pos27250419-27252552 --------------------------GACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGT-TGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT------------------------------------------------------------------------------------------------------------------------CTTAATTCCCATTCCATTCAGTGGCATTCAACCACACCATGCAC-CCTCCTGCAGCTCACTGTCCTTCTCTTGGAGAACTCTTGGTCTACTCACGAAGACAAATCTAATGCACAAGGCTCTGTTAGAGGTTACTACAAGGAAGTTCACTCCAAATATGCCAAGTCCAACGTGGACAAATGTCCAAGGTATAGAACAGAGAGAA--T------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATTCTGC-GGGGGGATG----------------AACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT-CCTGGCCTCAAGAGTCTGGATGT----------------------------CTGGGGAGTTTCA----------------------------------------------------------------------------------------- >AP19_unhealthy_ADIPOQ chr19_pos27250419-27252552 ------------------------CTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGATGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCAACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTGTAAAACCAGTGCCATTGACTCTGCTCTATCTACATCACC--CCCCATCTCCTT---------------CATCCATCCCTATTCCCAATCTGTTTATATT----------CTCATTTCCACTTAATTCCC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCAAGGTATAGAACAGAGAGAAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAGAGGGAACAGAAGAGCAAAAGTACAGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATGGA-GGTC--TGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAGTTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGC-CCCTGTTTCTCCTGATGTTCATGCCAGTCCTGTG-- >MC02_unhealthy_ADIPOQ chr19_pos27250419-27252552 ----------GTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTGCTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGGTTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGACTCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGGTTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCCCAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCGAGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAYGTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGACCTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATTCTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-TAAAACCAGTGCCATTGACTCTGCTCTATSTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTATTCC----------------TTATTTCTCCTCATTT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAGAGAAGG-----AATGAATTGATGGGATTCTGCTGGGGGGATGTGGAAGGAGGACGTKAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTTGCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACCTAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTTGTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGCTTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCAGCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACCAAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAACATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTCAGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAACTTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTCCAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACCTTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCACCACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAATGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCATTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATTCCCTGGCCTCAAGAGTCTGGATGTATTGGCAATG----------AACATTTAC---GGAGT-TCAGAT--------------------------------------------------------------------------------------

 

Multiple sequence alignment of consensus sequences derived for each healthy or unhealthy horse for the ADIPOQ' gene locus show no genetic mutation separating the two group of horses:

CLUSTAL multiple sequence alignment by MUSCLE (3.8) AP17_unhealthy_ADIPOQ -----------------------------------------GACTATGTGTGTGTGTGTG AP10_healthy_ADIPOQ ------------TCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP01_healthy_ADIPOQ ---------------TCGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP03_unhealthy_ADIPOQ -----------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG MC03_healthy_ADIPOQ --------------TCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP18_unhealthy_ADIPOQ -------------------------GACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP20_healthy_ADIPOQ --------TGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG MC01_healthy_ADIPOQ -------------------------------------------CTATGTGTGTGTGTGTG MC02_unhealthy_ADIPOQ ---------GTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP15_healthy_ADIPOQ ----------------------------TAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP02_healthy_ADIPOQ TGGGACAATGTG-CTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP07_healthy_ADIPOQ -----------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP14_unhealthy_ADIPOQ TGGGACAATGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP08_healthy_ADIPOQ -----------------------CTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP04_unhealthy_ADIPOQ -GGGACAATGTGTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP19_unhealthy_ADIPOQ -----------------------CTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG AP12_healthy_ADIPOQ -----------GTCTCTGGTTGTCTGACTAGATCAAGGAAAGACTATGTGTGTGTGTGTG ***************** AP17_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP10_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGG AP01_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGG AP03_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGG MC03_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP18_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGT-TGTATATGTATGTGTGTGTTTGGG AP20_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTRTGTGTGTGTTTGGG MC01_healthy_ADIPOQ CTTGTGCGT-CATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG MC02_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP15_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP02_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP07_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP14_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP08_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP04_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP19_unhealthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG AP12_healthy_ADIPOQ CTTGTGCGTACATGTGTGTGCAAGTATGTGTATGTATGTATATGTATGTGTGTGTTTGGG ********* ************************* ********* ************** AP17_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP10_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP01_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP03_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC MC03_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP18_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP20_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC MC01_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC MC02_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP15_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP02_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP07_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP14_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP08_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP04_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP19_unhealthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC AP12_healthy_ADIPOQ TTGGGTGTGCTGTTTGGGGTCTGCTCTCATGGCTGACAGTGCAGATTTGGATTCCAGGAC ************************************************************ AP17_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP10_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP01_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP03_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG MC03_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP18_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP20_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG MC01_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG MC02_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP15_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP02_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP07_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP14_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP08_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP04_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP19_unhealthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG AP12_healthy_ADIPOQ TCAGGATGCTGTTGCTCCAAGCTGTTCTATTGCTACTAGTCCTGCCGAGTCCGGGTGAGG ************************************************************ AP17_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP10_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP01_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP03_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC MC03_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP18_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP20_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC MC01_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC MC02_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP15_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP02_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP07_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP14_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP08_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP04_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP19_unhealthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC AP12_healthy_ADIPOQ TTACCACGACTGAAGAGACTCTGCCCAAGGAGGGCTGCGCAGGTTGGATGGCAGGCATCC ************************************************************ AP17_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP10_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCG AP01_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCG AP03_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGYGATGGCAGAGATGGCACCCCTGGCG MC03_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP18_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP20_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGCGATGGCAGAGATGGCACCCCTGGCG MC01_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG MC02_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP15_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP02_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP07_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP14_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP08_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP04_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP19_unhealthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG AP12_healthy_ADIPOQ CAGGGCATCCTGGCCACAATGGGACCCCAGGCCGTGATGGCAGAGATGGCACCCCTGGCG ********************************** ************************* AP17_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP10_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP01_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP03_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT MC03_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP18_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP20_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT MC01_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT MC02_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAY AP15_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP02_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP07_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP14_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP08_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAY AP04_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAY AP19_unhealthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT AP12_healthy_ADIPOQ AGAAGGGTGAGAAAGGAGATCCAGGTAAGAACAAGGTTTTTGGCCTCTTCCATCACAGAT *********************************************************** AP17_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGAC-AGGGCATTAGTTATCRACTCAGAC AP10_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP01_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC AP03_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC MC03_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP18_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC AP20_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC MC01_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC MC02_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP15_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC AP02_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC AP07_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP14_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP08_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCGACTCAGAC AP04_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCRACTCAGAC AP19_unhealthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCAACTCAGAC AP12_healthy_ADIPOQ GTCTCCTGGGTATAGGAGGGCTTCTAGAATTAGACTAGGGCATTAGTTATCAACTCAGAC *********************************** *************** ******** AP17_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP10_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP01_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP03_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGC-ACCTGAAGTGAATT MC03_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP18_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP20_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT MC01_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT MC02_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP15_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP02_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP07_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP14_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP08_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP04_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP19_unhealthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT AP12_healthy_ADIPOQ CTAGTTATGGGGAAGAAGCAAAGCTTTTTTATGTGACTTACGAGCAACCTGAAGTGAATT ********************************************* ************** AP17_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAG-TGTTATCT-GTAAAACCAGTGCCATTGAC- AP10_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP01_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP03_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT MC03_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP18_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCTCTTAATTCCCATTCCATTCAGT AP20_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT MC01_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-G-------------------- MC02_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT--TAAAACCAGTGCCATTGACT AP15_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP02_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP07_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP14_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP08_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP04_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP19_unhealthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT AP12_healthy_ADIPOQ CTGGGTTGGCTTTCTGGTGCTGAGAATAGATGTTATCT-GTAAAACCAGTGCCATTGACT ***************************** ******** AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCC---CTCATCCATCCCT- AP01_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP03_unhealthy_ADIPOQ CTGC-CTATCTAC-TCACCCTCCCACCCTCCC------CCCCCTCTTTCTTATATTTTAT MC03_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP18_unhealthy_ADIPOQ GGCATTCAACCACACCATGCACCCTCCTGCAGCTCACTGTCCTTCTCTTGGAGAACTCTT AP20_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCT--- MC01_healthy_ADIPOQ ------------------------------------------------------------ MC02_unhealthy_ADIPOQ CTGCTCTATSTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP15_healthy_ADIPOQ CTGCTTTCTCATCA-----CTCCCCATCTCCTTTCCC-CCCCCACTTCCATCCATCCCTA AP02_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP07_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP14_unhealthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP08_healthy_ADIPOQ ------------------------------------------------------------ AP04_unhealthy_ADIPOQ CTGCTCTATSTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP19_unhealthy_ADIPOQ CTGCTCTATCTACATCACC--CCCCATCTCCTT---------------CATCCATCCCTA AP12_healthy_ADIPOQ CTGCTCTATCTACATCACCCTCCCCATCTCCTTTCCCACCCCCACTTCCATCCATCCCTA AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ ------------------------------------------------------------ AP01_healthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP03_unhealthy_ADIPOQ TCTCCA------------------------------------------------------ MC03_healthy_ADIPOQ TTCCACTGTTTTCTA--------TTTCTCCTCTT-------------------------- AP18_unhealthy_ADIPOQ GGTCTACT---------------------------------------------------- AP20_healthy_ADIPOQ TTCCCACTTTATTTCT-------TTTCTCCTCATTT------------------------ MC01_healthy_ADIPOQ ------------------------------------------------------------ MC02_unhealthy_ADIPOQ TTCC----------------TTATTTCTCCTCATTT------------------------ AP15_healthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP02_healthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP07_healthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP14_unhealthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP08_healthy_ADIPOQ ------------------------TTCTCCTCATTTCCACTTAATTCCCATTCCA----- AP04_unhealthy_ADIPOQ TTCCCAATCTGTTTATATTCTTATTTCTCCTCATTTCCACTTAATTCCCATTCCATTCAG AP19_unhealthy_ADIPOQ TTCCCAATCTGTTTATATT----------CTCATTTCCACTTAATTCCC----------- AP12_healthy_ADIPOQ TTCCCAATCTGTTAA--------------------------------------------- AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ ------------------------------------------------------------ AP01_healthy_ADIPOQ TGGCATTCAACCACACCATGCACACCTCC------------------------------- AP03_unhealthy_ADIPOQ ------------------------------------------------------------ MC03_healthy_ADIPOQ ------------------------------------------------------------ AP18_unhealthy_ADIPOQ ------------------------------------------------------------ AP20_healthy_ADIPOQ ------------------------------------------------------------ MC01_healthy_ADIPOQ ------------------------------------------------------------ MC02_unhealthy_ADIPOQ ------------------------------------------------------------ AP15_healthy_ADIPOQ TGGCATTCAACCACACCATGCACACCTCC------------------------------- AP02_healthy_ADIPOQ TGGCATTCAACCACATCAA----------------------------------------- AP07_healthy_ADIPOQ TGGCAT------------------------------------------------------ AP14_unhealthy_ADIPOQ TGGCATTCAACCACACCATGCACACCTCCTGCAGCTCACTGTCCTTCTCTTGGAGAACTC AP08_healthy_ADIPOQ ------------------------------------------------------------ AP04_unhealthy_ADIPOQ TGGCATTCAACCACACCATGCACACCTCCTGCAGC-CACTGTCCTTCTCTTGGAGAACTC AP19_unhealthy_ADIPOQ ------------------------------------------------------------ AP12_healthy_ADIPOQ ------------------------------------------------------------ AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ ------------------------------------------------------------ AP01_healthy_ADIPOQ ------------------------------------------------------------ AP03_unhealthy_ADIPOQ ------------------------------------------------------------ MC03_healthy_ADIPOQ ------------------------------------------------------------ AP18_unhealthy_ADIPOQ ------------------------------------------------------------ AP20_healthy_ADIPOQ ------------------------------------------------------------ MC01_healthy_ADIPOQ ------------------------------------------------------------ MC02_unhealthy_ADIPOQ ------------------------------------------------------------ AP15_healthy_ADIPOQ ------------------------------------------------------------ AP02_healthy_ADIPOQ ------------------------------------------------------------ AP07_healthy_ADIPOQ ------------------------------------------------------------ AP14_unhealthy_ADIPOQ TTGGTCTACTCACGAAGACAAATCTAATGCACAAGGCTCTGTTAGAGGTTACTACAAGGA AP08_healthy_ADIPOQ ------------------------------------------------------------ AP04_unhealthy_ADIPOQ TTGGTCTACTCACGAAGACAAATCTAATGCACAAGGCTCTGTT--GAGTTACTACAAGGA AP19_unhealthy_ADIPOQ ------------------------------------------------------------ AP12_healthy_ADIPOQ ------------------------------------------------------------ AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ ------------------------------------------------------------ AP01_healthy_ADIPOQ ------------------------------------------------------------ AP03_unhealthy_ADIPOQ ------------------------------------------------------------ MC03_healthy_ADIPOQ -----------------------------------------------------CCGAGAG AP18_unhealthy_ADIPOQ ------------------------------------------------------------ AP20_healthy_ADIPOQ -------------------------------GACAAATGTCCAAGGTATAGAACAGAGAG MC01_healthy_ADIPOQ ------------------------------------------------------------ MC02_unhealthy_ADIPOQ ------------------------------------------------------------ AP15_healthy_ADIPOQ ------------------------------------------------------------ AP02_healthy_ADIPOQ ------------------------------------------------------------ AP07_healthy_ADIPOQ ---------------------------------------------------AACAGGG-- AP14_unhealthy_ADIPOQ AGTTCACTCCAAATATGCCAAGTCCAACGTGGACAAATGTCCAAGGTATAGAACAGAGAG AP08_healthy_ADIPOQ ------------------------------------------------------------ AP04_unhealthy_ADIPOQ AGTTCACTCCAAATATGCCAAGTCCAACGTGGAC-AATGTCCAAGGTATAGAACAGAGAG AP19_unhealthy_ADIPOQ ----------------------------------------CCAAGGTATAGAACAGAGAG AP12_healthy_ADIPOQ ------------------------------------------------------------ AP17_unhealthy_ADIPOQ ---------------------------------GAAGGCTTCAAAGAGGAGGGGGAACAG AP10_healthy_ADIPOQ ---------------------------------------CCAGGAGATTAGCCAGCACAT AP01_healthy_ADIPOQ -------------TGCAGCTC-------------AAGGCTTCAAAGAGGAGGCAGTACCG AP03_unhealthy_ADIPOQ ------------------------------------------------GGGGCAGGGCAG MC03_healthy_ADIPOQ AAAATG-------TGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG AP18_unhealthy_ADIPOQ -------------CACGAAGACAAATCTAATGCACAAGGCTCTGTTAGAGGTTACTACAA AP20_healthy_ADIPOQ AAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG MC01_healthy_ADIPOQ --------------------------------------GCTCAAAGAGGAGGCA------ MC02_unhealthy_ADIPOQ ------------------------------------------------------------ AP15_healthy_ADIPOQ -------------TGCAGCTC--------------------------------------- AP02_healthy_ADIPOQ -------------TGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG AP07_healthy_ADIPOQ ----TGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAA--AGGGGGCAGGGCAG AP14_unhealthy_ADIPOQ AAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG AP08_healthy_ADIPOQ ---------------------------------GAAGGCTTCAAAGAGGAGG-AGGGCAG AP04_unhealthy_ADIPOQ AAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG AP19_unhealthy_ADIPOQ AAAATGCCCTCAATGCAGGCCTGGATTAAAAATGAAGGCTTCAAAGAGGAGGCAGGGCAG AP12_healthy_ADIPOQ -------------TGCAGGCC---------------------------GAGGCAGGGCAG AP17_unhealthy_ADIPOQ AAGGCA------------------------------------------------------ AP10_healthy_ADIPOQ AAAGGGT--------------------------------------------GGGGGCATG AP01_healthy_ADIPOQ AAAGGGT--------------------------------------------GGGGGCATG AP03_unhealthy_ADIPOQ AGGGAACAGAAG---------------------------------------GGGGGCATG MC03_healthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAG-CAGCACATAAAGGGTTGGGGGCATG AP18_unhealthy_ADIPOQ GGAAGTT-----------------------------CACTCCAAATATGCCAAGTCCAAC AP20_healthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGG---GGGGGGCTG MC01_healthy_ADIPOQ --GGAACAGAAGAGCAA------------------------------------------- MC02_unhealthy_ADIPOQ ------------------------------------------------------------ AP15_healthy_ADIPOQ ------------------------------------------------------------ AP02_healthy_ADIPOQ AGGGAACA-AAGAGCAAAAGTACRGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATG AP07_healthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATG AP14_unhealthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACGGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATG AP08_healthy_ADIPOQ AGGGAACAGAA------------------------------------------------- AP04_unhealthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACRGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATG AP19_unhealthy_ADIPOQ AGGGAACAGAAGAGCAAAAGTACAGTTGGTTGAGCCAGCACATAAAGGGTTGGGGGCATG AP12_healthy_ADIPOQ AGGGAACAG------------------------------------------GGGGGCATT AP17_unhealthy_ADIPOQ ------------------------------------------AAGTCGTTGGGA------ AP10_healthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP01_healthy_ADIPOQ GAGGG-CTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP03_unhealthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGG-GAGAAGGTTAGCAATGAATTGATGGGATTCTGC MC03_healthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP18_unhealthy_ADIPOQ GTGGACAAATGTCCAAGGTATAGAACAGAGAGAAT------------------ATTCTGC AP20_healthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC MC01_healthy_ADIPOQ -AGTACGTTGGTTGAGGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC MC02_unhealthy_ADIPOQ -------------------------GAGAGAAGG-----AATGAATTGATGGGATTCTGC AP15_healthy_ADIPOQ --------ATGATGG-GACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP02_healthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP07_healthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP14_unhealthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP08_healthy_ADIPOQ --------------GAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP04_unhealthy_ADIPOQ GAGGGTCTATGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP19_unhealthy_ADIPOQ GAGG---TCTGATGGAGACTTATAGGAGAGAAGGTTAGCAATGAATTGATGGGATTCTGC AP12_healthy_ADIPOQ -------------------------GGGAGAAGGTTAGCAATGAATTGATGGGATTCTGC * AP17_unhealthy_ADIPOQ -------------GAGGAGGACGT----------CCTTTGGGAGCTCCCATTGGTTCCTT AP10_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP01_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP03_unhealthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT MC03_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGG-CGTGAAACTCT-CCCTTTGGGAGCTCCCATTGGTTCCTT AP18_unhealthy_ADIPOQ -GGGGGGATG----------------AACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP20_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT MC01_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGT-AAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT MC02_unhealthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTKAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP15_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGAC-TGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP02_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP07_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP14_unhealthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP08_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCT-CCATTGGTTCCTT AP04_unhealthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP19_unhealthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT AP12_healthy_ADIPOQ TGGGGGGATGTGGAAGGAGGACGTGAAACTCTCCCCTTTGGGAGCTCCCATTGGTTCCTT ************ ************* AP17_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP10_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP01_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP03_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC MC03_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP18_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP20_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC MC01_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC MC02_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP15_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP02_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP07_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP14_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP08_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP04_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP19_unhealthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC AP12_healthy_ADIPOQ GCTCTGTAAGTCAAACAGGTTGTGAGAAGGCTCCATAGGGACAGTGTTTTAGGCTGGACC ************************************************************ AP17_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCC-TTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP10_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP01_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP03_unhealthy_ADIPOQ TARCCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT MC03_healthy_ADIPOQ TARCCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP18_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP20_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT MC01_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT MC02_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP15_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP02_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP07_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP14_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCYTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP08_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP04_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP19_unhealthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT AP12_healthy_ADIPOQ TAACCTAGGCAGGAGTTCTGTCCCTTGTAGTCACTGAAGTCTGCTCCTTCCCTAGGTCTT ** ******************** ************************************ AP17_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP10_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP01_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP03_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC MC03_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP18_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP20_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC MC01_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC MC02_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP15_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP02_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP07_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP14_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP08_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP04_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP19_unhealthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC AP12_healthy_ADIPOQ GTTGGGCCTAAGGGTGATGCTGGTGAAACTGGAGTGCCTGGAGTTGAAGGTCCCAGAGGC ************************************************************ AP17_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP10_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP01_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP03_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA MC03_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP18_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP20_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA MC01_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA MC02_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP15_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP02_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP07_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP14_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP08_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP04_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP19_unhealthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA AP12_healthy_ADIPOQ TTTCCGGGAATCCCAGGCAGGAAAGGAGAACCTGGAGAAAGTTCCTATGTATACCGCTCA ************************************************************ AP17_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP10_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP01_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP03_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC MC03_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP18_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP20_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC MC01_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC MC02_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP15_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP02_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP07_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP14_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP08_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP04_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP19_unhealthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC AP12_healthy_ADIPOQ GCATTCAGTGTAGGATTGGAGACCCGAGTCACCGTCCCCAATGTTCCCATTCGTTTTACC ************************************************************ AP17_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP10_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP01_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP03_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC MC03_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP18_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP20_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC MC01_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC MC02_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP15_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP02_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP07_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP14_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP08_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP04_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP19_unhealthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC AP12_healthy_ADIPOQ AAGATCTTCTACAATCAGCAAAACCACTATGATGGCAGCACGGGCAAATTCCACTGCAAC ************************************************************ AP17_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP10_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP01_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP03_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC MC03_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP18_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP20_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC MC01_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC MC02_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP15_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP02_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP07_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP14_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP08_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP04_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP19_unhealthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC AP12_healthy_ADIPOQ ATTCCTGGGCTGTACTACTTCTCCTACCACATCACAGTCTACTTGAAGGATGTGAAGGTC ************************************************************ AP17_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP10_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP01_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP03_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC MC03_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP18_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP20_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC MC01_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC MC02_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP15_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP02_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP07_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP14_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP08_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP04_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP19_unhealthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC AP12_healthy_ADIPOQ AGCCTCTACAAGAAGGACAAGGCTGTGCTCTTCACCTATGACCAGTACCAGGACAAGAAC ************************************************************ AP17_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP10_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP01_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP03_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC MC03_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP18_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP20_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC MC01_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC MC02_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP15_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP02_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP07_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP14_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP08_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP04_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP19_unhealthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC AP12_healthy_ADIPOQ TTGGACCAGGCCTCAGGCTCTGTTCTCCTCTATCTGGAGAAGGGCGACCAAGTCTGGCTC ************************************************************ AP17_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP10_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP01_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP03_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC MC03_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP18_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP20_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC MC01_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC MC02_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP15_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP02_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP07_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP14_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP08_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP04_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP19_unhealthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC AP12_healthy_ADIPOQ CAGGTGTATGGGGATGGAGATCATAATGGGCTCTATGCCGATAATGTCAATGACTCCACC ************************************************************ AP17_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP10_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP01_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP03_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC MC03_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP18_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP20_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC MC01_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC MC02_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP15_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP02_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP07_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP14_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP08_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP04_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP19_unhealthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC AP12_healthy_ADIPOQ TTCACAGGCTTCCTTCTCTACCACGACACCAACTGATTACCACTAACTCAGAGCCTCCAC ************************************************************ AP17_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP10_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP01_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP03_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA MC03_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP18_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP20_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA MC01_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA MC02_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP15_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP02_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP07_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP14_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP08_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP04_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP19_unhealthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA AP12_healthy_ADIPOQ CACGCCAAACAGCCCAAAAGTCAAAGAACAGTCCACAGGTTTCCATTGTAGTTAGGAAAA ************************************************************ AP17_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTA-TCATTCATTCA AP10_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP01_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP03_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA MC03_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP18_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP20_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA MC01_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA MC02_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP15_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP02_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP07_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP14_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP08_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP04_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP19_unhealthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA AP12_healthy_ADIPOQ TGATTTTATTATCTAGTTGGAGGGCTCTGAACATTAGTCACTCATTTACTCATTCATTCA ************************************************ *********** AP17_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP10_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP01_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP03_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT MC03_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP18_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP20_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT MC01_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT MC02_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP15_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP02_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP07_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP14_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP08_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP04_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP19_unhealthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT AP12_healthy_ADIPOQ TTTACCAAGTACCTTTAAAAAAATCATATATTGTGTTCCCAGTCCTGAAGAAGACATATT ************************************************************ AP17_unhealthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAA---------------------------- AP10_healthy_ADIPOQ CCCTGGCYTCAAGAGTCTGGRTGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGA- AP01_healthy_ADIPOQ CCCTGGCYTCAAGAGTCTGGRTGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP03_unhealthy_ADIPOQ CCCTGGCYTCAAGAGTCTGG-TGTATTGGCAATGAAAGGATGGTAAC------------- MC03_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATG-AAGGATGGTAACATTTACTGGGGAG AP18_unhealthy_ADIPOQ -CCTGGCCTCAAGAGTCTGGATGT----------------------------CTGGGGAG AP20_healthy_ADIPOQ CCCTGGCTTCAAGAGTCTGGGTGTATTGGCAATG-AAGGATGGTAACATTTACTGGGGAG MC01_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG MC02_unhealthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATG----------AACATTTACGGAG--- AP15_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP02_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP07_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP14_unhealthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP08_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP04_unhealthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP19_unhealthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG AP12_healthy_ADIPOQ CCCTGGCCTCAAGAGTCTGGATGTATTGGCAATGAAAGGATGGTAACATTTACTGGGGAG ****** ************ *** AP17_unhealthy_ADIPOQ ------------------------------------------------------------ AP10_healthy_ADIPOQ -TTCAGATAC-------------------------------------------------- AP01_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCC- AP03_unhealthy_ADIPOQ ------------------------------------------------------------ MC03_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP18_unhealthy_ADIPOQ TTTCA------------------------------------------------------- AP20_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAG------------------------------ MC01_healthy_ADIPOQ TTTCAGATACATGACAAGATAAC-----------------ACAAAGCTTCGCAATC---- MC02_unhealthy_ADIPOQ -TTCAGAT---------------------------------------------------- AP15_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP02_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP07_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP14_unhealthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP08_healthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAG------------------------------ AP04_unhealthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCCC AP19_unhealthy_ADIPOQ TTTCAGATACATGACAAGATAAACTACAAGAAAGTCTTCGACAATGCTATTCTGTGCCC- AP12_healthy_ADIPOQ TTTCAGATACATG----------------------------------------------- AP17_unhealthy_ADIPOQ ---------------------------------- AP10_healthy_ADIPOQ ---------------------------------- AP01_healthy_ADIPOQ ---------------------------------- AP03_unhealthy_ADIPOQ ---------------------------------- MC03_healthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCGTCGG------ AP18_unhealthy_ADIPOQ ---------------------------------- AP20_healthy_ADIPOQ ---------------------------------- MC01_healthy_ADIPOQ ---------------------------------- MC02_unhealthy_ADIPOQ ---------------------------------- AP15_healthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCAGTCCTG---- AP02_healthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCA---------- AP07_healthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG AP14_unhealthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG AP08_healthy_ADIPOQ ---------------------------------- AP04_unhealthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCAGTCCTGTGAG AP19_unhealthy_ADIPOQ CTGTTTCTCCTGATGTTCATGCCAGTCCTGTG-- AP12_healthy_ADIPOQ ----------------------------------

 

Predicted single-nucleotide variants:

GROUP

SAMPLE  

#CHROM  

POS    

 ID      

REF     

ALT     

QUAL    

FILTER  

INFO    

FORMAT

healthy

AP15

19

9

A

G

4.38466

PASS

DP=12;SGB=-0.379885;MQ0F=0;AC=2;AN=2;DP4=0,0,1,0;MQ=60

GT:PL

1/1:32,3,0

healthy

AP01

19

107

A

G

70

PASS

DP=107;VDB=0.432988;SGB=-0.670168;RPB=0.692565;MQB=0.479682;MQSB=0.885379;BQB=0.619651;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=54,4,9,1;MQ=56

GT:PL

0/1:106,0,255

healthy

AP10

19

107

A

G

222

PASS

DP=138;VDB=0.400335;SGB=-0.693054;RPB=0.999783;MQB=0.000239681;MQSB=0.768939;BQB=0.358561;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=47,3,27,1;MQ=54

GT:PL

0/1:255,0,255

healthy

AP20

19

107

A

G

222

PASS

DP=214;VDB=8.22792e-06;SGB=-0.693147;RPB=4.61987e-07;MQB=5.88647e-17;MQSB=0.727273;BQB=9.14987e-06;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=49,1,72,1;MQ=55

GT:PL

0/1:255,0,255

unhealthy

AP03

19

107

A

G

126

PASS

DP=179;VDB=0.0380618;SGB=-0.692562;RPB=0.00426831;MQB=5.47917e-07;MQSB=0.756028;BQB=0.0105446;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=73,4,20,2;MQ=50

GT:PL

0/1:160,0,255

healthy

AP01

19

336

T

C

222

PASS

DP=226;VDB=0.892467;SGB=-0.693147;RPB=0.000600842;MQB=1;MQSB=1;BQB=0.7471;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=42,59,41,37;MQ=60

GT:PL

0/1:255,0,255

healthy

AP10

19

336

T

C

222

PASS

DP=211;VDB=0.932776;SGB=-0.693147;RPB=0.694454;MQB=0.989796;MQSB=0.988977;BQB=0.99676;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=51,29,32,43;MQ=59

GT:PL

0/1:255,0,255

healthy

AP20

19

336

T

C

225

PASS

DP=235;VDB=0.293902;SGB=-0.693147;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,82,107;MQ=60

GT:PL

1/1:255,255,0

unhealthy

AP03

19

336

T

C

222

PASS

DP=142;VDB=0.999996;SGB=-0.693147;RPB=0.930953;MQB=1;MQSB=1;BQB=0.740136;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=28,26,23,28;MQ=60

GT:PL

0/1:255,0,255

healthy

AP08

19

421

T

C

222

PASS

DP=64;VDB=0.287107;SGB=-0.692717;RPB=0.366828;MQB=1;MQSB=1;BQB=0.999854;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=8,24,10,13;MQ=60

GT:PL

0/1:255,0,255

unhealthy

AP04

19

421

T

C

222

PASS

DP=228;VDB=0.000427982;SGB=-0.693147;RPB=0.000184404;MQB=1;MQSB=1;BQB=0.53987;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=19,109,12,70;MQ=60

GT:PL

0/1:255,0,255

healthy

AP01

19

473

A

G

222

PASS

DP=96;VDB=0.0441685;SGB=-0.693139;RPB=0.0340648;MQB=1;MQSB=1;BQB=0.913127;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=4,49,4,32;MQ=60

GT:PL

0/1:255,0,255

healthy

AP02

19

473

A

G

222

PASS

DP=119;VDB=0.000827741;SGB=-0.693147;RPB=0.00523428;MQB=1;MQSB=1;BQB=0.911665;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=3,52,3,49;MQ=60

GT:PL

0/1:255,0,255

healthy

AP07

19

473

A

G

225

PASS

DP=65;VDB=0.999123;SGB=-0.693147;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,6,51;MQ=60

GT:PL

1/1:255,172,0

healthy

AP08

19

473

A

G

225

PASS

DP=39;VDB=0.985983;SGB=-0.693141;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,3,34;MQ=60

GT:PL

1/1:255,111,0

healthy

AP10

19

473

A

G

225

PASS

DP=57;VDB=0.278336;SGB=-0.693147;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,2,51;MQ=60

GT:PL

1/1:255,160,0

healthy

AP15

19

473

A

G

145

PASS

DP=35;VDB=0.630539;SGB=-0.69168;RPB=0.794216;MQB=1;MQSB=1;BQB=0.0538474;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=1,15,0,19;MQ=60

GT:PL

0/1:178,0,215

healthy

AP20

19

473

A

G

225

PASS

DP=107;VDB=0.821122;SGB=-0.693147;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,11,84;MQ=60

GT:PL

1/1:255,255,0

healthy

MC01

19

473

A

G

206

PASS

DP=31;VDB=0.63001;SGB=-0.686358;RPB=0.412321;MQB=1;MQSB=1;BQB=0.940868;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,15,2,12;MQ=60

GT:PL

0/1:239,0,182

healthy

MC03

19

473

A

G

225

PASS

DP=48;VDB=0.949858;SGB=-0.693146;MQSB=0.995736;MQ0F=0;AC=2;AN=2;DP4=0,0,5,39;MQ=59

GT:PL

1/1:255,132,0

unhealthy

AP03

19

473

A

G

225

PASS

DP=43;VDB=0.43904;SGB=-0.693139;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,5,31;MQ=60

GT:PL

1/1:255,108,0

unhealthy

AP04

19

473

A

G

222

PASS

DP=176;VDB=0.0813466;SGB=-0.693147;RPB=1.50428e-05;MQB=1;MQSB=1;BQB=0.922309;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=5,92,9,61;MQ=60

GT:PL

0/1:255,0,255

unhealthy

AP14

19

473

A

G

225

PASS

DP=166;VDB=0.00337137;SGB=-0.693147;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,5,148;MQ=60

GT:PL

1/1:255,255,0

unhealthy

AP17

19

473

A

G

222

PASS

DP=23;VDB=0.872319;SGB=-0.676189;RPB=0.930391;MQB=1;MQSB=1;BQB=0.142141;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,9,2,9;MQ=60

GT:PL

0/1:255,0,145

unhealthy

AP18

19

473

A

G

181

PASS

DP=31;VDB=0.0889763;SGB=-0.688148;RPB=0.765017;MQB=1;MQSB=1;BQB=0.295511;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=3,9,1,14;MQ=60

GT:PL

0/1:214,0,255

unhealthy

AP04

19

610

C

G

42.1225

PASS

DP=47;VDB=0.906964;SGB=-0.616816;RPB=0.0223322;MQB=1;MQSB=1;BQB=0.497442;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=2,27,0,6;MQ=60

GT:PL

0/1:77,0,245

healthy

AP01

19

984

A

G

18.4251

PASS

DP=6;SGB=-0.379885;RPB=1;MQB=1;BQB=1;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=2,0,1,0;MQ=60

GT:PL

0/1:51,0,59

healthy

AP02

19

984

A

G

98

PASS

DP=13;VDB=0.978871;SGB=-0.616816;RPB=0.623736;MQB=0.961166;BQB=0.899815;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=7,0,6,0;MQ=60

GT:PL

0/1:131,0,142

healthy

AP07

19

984

A

G

199

PASS

DP=16;VDB=0.657642;SGB=-0.688148;MQ0F=0;AC=2;AN=2;DP4=0,0,15,0;MQ=60

GT:PL

1/1:229,45,0

healthy

AP08

19

984

A

G

85

PASS

DP=4;VDB=0.663511;SGB=-0.511536;MQ0F=0;AC=2;AN=2;DP4=0,0,3,0;MQ=60

GT:PL

1/1:115,9,0

healthy

AP10

19

984

A

G

70

PASS

DP=3;VDB=0.519801;SGB=-0.511536;MQ0F=0;AC=2;AN=2;DP4=0,0,3,0;MQ=60

GT:PL

1/1:100,9,0

healthy

AP20

19

984

A

G

142

PASS

DP=8;VDB=0.789228;SGB=-0.616816;MQ0F=0;AC=2;AN=2;DP4=0,0,6,0;MQ=60

GT:PL

1/1:172,18,0

healthy

MC01

19

984

A

G

28.2608

PASS

DP=5;VDB=0.02;SGB=-0.453602;RPB=0;MQB=1;BQB=0.666667;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=3,0,2,0;MQ=60

GT:PL

0/1:61,0,87

healthy

MC03

19

984

A

G

127

PASS

DP=6;VDB=0.0901919;SGB=-0.616816;MQ0F=0;AC=2;AN=2;DP4=0,0,6,0;MQ=60

GT:PL

1/1:157,18,0

unhealthy

AP03

19

984

A

G

72

PASS

DP=3;VDB=0.724364;SGB=-0.511536;MQ0F=0;AC=2;AN=2;DP4=0,0,3,0;MQ=60

GT:PL

1/1:102,9,0

unhealthy

AP04

19

984

A

G

147

PASS

DP=74;VDB=0.000218599;SGB=-0.69311;RPB=0.0460096;MQB=1;MQSB=1;BQB=0.83398;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=42,1,31,0;MQ=60

GT:PL

0/1:180,0,229

unhealthy

AP14

19

984

A

G

225

PASS

DP=48;VDB=0.693034;SGB=-0.69311;MQSB=1;MQ0F=0;AC=2;AN=2;DP4=0,0,27,4;MQ=60

GT:PL

1/1:255,93,0

unhealthy

AP18

19

984

A

G

11.7172

PASS

DP=2;SGB=-0.379885;MQ0F=0;AC=2;AN=2;DP4=0,0,0,1;MQ=60

GT:PL

1/1:41,3,0

healthy

MC01

19

1105

G

T

144

PASS

DP=22;VDB=2.99077e-05;SGB=-0.692067;RPB=1;MQB=1;MQSB=1;BQB=1;MQ0F=0;AC=2;AN=2;DP4=0,1,20,0;MQ=60

GT:PL

1/1:171,3,0

healthy

MC03

19

1203

A

G

222

PASS

DP=59;VDB=0.157838;SGB=-0.692831;RPB=0.556584;MQB=1;MQSB=1;BQB=0.897968;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=20,4,18,6;MQ=60

GT:PL

0/1:255,0,255

unhealthy

AP03

19

1203

A

G

222

PASS

DP=62;VDB=0.0526789;SGB=-0.692067;RPB=0.254155;MQB=1;MQSB=1;BQB=0.742786;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=30,2,16,4;MQ=60

GT:PL

0/1:255,0,255

healthy

AP02

19

1224

C

T

222

PASS

DP=144;VDB=0.00561792;SGB=-0.693147;RPB=0.00099301;MQB=1;MQSB=1;BQB=0.624884;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=55,7,58,13;MQ=60

GT:PL

0/1:255,0,255

healthy

AP07

19

1224

C

T

222

PASS

DP=80;VDB=0.0657575;SGB=-0.693127;RPB=0.226443;MQB=1;MQSB=1;BQB=0.715342;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=28,10,23,10;MQ=60

GT:PL

0/1:255,0,255

healthy

AP10

19

1224

C

T

222

PASS

DP=104;VDB=0.00271413;SGB=-0.693147;RPB=0.933896;MQB=0.975257;MQSB=0.994638;BQB=0.999242;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=27,7,35,11;MQ=59

GT:PL

0/1:255,0,255

healthy

MC01

19

1224

C

T

222

PASS

DP=62;VDB=0.121716;SGB=-0.689466;RPB=0.972875;MQB=1;MQSB=1;BQB=0.233506;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=31,2,11,5;MQ=60

GT:PL

0/1:255,0,255

unhealthy

AP14

19

1224

C

T

222

PASS

DP=251;VDB=0.461073;SGB=-0.693147;RPB=0.00193556;MQB=1;MQSB=1;BQB=0.999748;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=107,19,82,6;MQ=60

GT:PL

0/1:255,0,255

unhealthy

AP18

19

1224

C

T

185

PASS

DP=46;VDB=0.000262524;SGB=-0.689466;RPB=0.769244;MQB=1;MQSB=1;BQB=0.253947;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=18,4,15,1;MQ=60

GT:PL

0/1:218,0,255

unhealthy

AP17

19

1909

C

T

14.8883

PASS

DP=50;VDB=0.0221621;SGB=-0.511536;RPB=0.624865;MQB=0.995309;MQSB=1.06012e-05;BQB=0.39787;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=15,14,3,0;MQ=52

GT:PL

0/1:51,0,255

healthy

AP01

19

1988

C

T

191

PASS

DP=44;VDB=0.0448212;SGB=-0.692352;RPB=0.000197434;MQB=1;MQSB=1;BQB=0.107093;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,22,1,20;MQ=60

GT:PL

0/1:224,0,183

healthy

AP10

19

1988

C

T

189

PASS

DP=31;VDB=0.00716827;SGB=-0.690438;RPB=0.94723;MQB=0.923174;MQSB=0.5;BQB=0.613901;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=1,10,1,16;MQ=59

GT:PL

0/1:222,0,192

healthy

AP20

19

1988

C

T

184

PASS

DP=20;VDB=0.172079;SGB=-0.690438;MQ0F=0;AC=2;AN=2;DP4=0,0,0,17;MQ=60

GT:PL

1/1:214,51,0

unhealthy

AP03

19

1988

C

T

63

PASS

DP=12;VDB=0.803107;SGB=-0.556411;RPB=0.697274;MQB=1;BQB=0.94394;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,8,0,4;MQ=60

GT:PL

0/1:96,0,158

healthy

AP01

19

2001

A

G

195

PASS

DP=31;VDB=0.00546359;SGB=-0.692067;RPB=0.0153577;MQB=1;MQSB=1;BQB=0.953191;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,11,1,19;MQ=60

GT:PL

0/1:228,0,154

healthy

AP10

19

2001

A

G

176

PASS

DP=18;VDB=0.00533949;SGB=-0.683931;RPB=0.585302;MQB=1;MQSB=1;BQB=0.615186;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,5,1,12;MQ=60

GT:PL

0/1:209,0,104

healthy

AP20

19

2001

A

G

180

PASS

DP=15;VDB=0.112046;SGB=-0.688148;MQ0F=0;AC=2;AN=2;DP4=0,0,0,15;MQ=60

GT:PL

1/1:210,45,0

unhealthy

AP03

19

2001

A

G

14.9424

PASS

DP=9;VDB=0.86;SGB=-0.453602;RPB=1;MQB=1;BQB=1;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=0,7,0,2;MQ=60

GT:PL

0/1:49,0,151

unhealthy

AP17

19

2016

A

C

5.69441

PASS

DP=6;SGB=-0.379885;RPB=1;MQB=1;MQSB=0.5;BQB=1;MQ0F=0;ICB=1;HOB=0.5;AC=1;AN=2;DP4=1,2,1,0;MQ=57

GT:PL

0/1:38,0,120